Titan A.E.

Titan A.E. is a 2000 American animated post-apocalyptic science fiction action film directed by Don Bluth and Gary Goldman, and starring Matt Damon, Bill Pullman, John Leguizamo, Nathan Lane, Janeane Garofalo, and Drew Barrymore. Its title refers to the spacecraft central to the plot with A.E. meaning "After Earth". The animation of the film combines traditional hand-drawn created animation with the extensive use of computer-generated imagery.

Synopsis from Wikipedia, CC BY-SA 4.0. Everything below written here.

Poster © the film's rights holders.